28.8 Multi-Modal Peripheral Nerve Active Probe and Microstimulator with On-Chip Dual-Coil Power/Data Transmission and 64 2<sup>nd</sup>-Order Opamp-Less ΔΣ ADCs
Maged ElAnsary, Jianxiong Xu, José Sales Filho, Gairik Dutta, Liam Long, Aly Shoukry, Camilo Tejeiro, Chenxi Tang, Enver G. Kilinc, Jaimin Joshi, Parisa Sabetian, Samantha Unger, José Zariffa, Paul B. Yoo, Roman Genov
Abstract
The peripheral nervous system (PNS) enables communication between the central nervous system and various organs, for example by conveying sensory information and relaying motor commands. Electrical stimulation of peripheral nerves has been shown effective in treating major intractable disorders ranging from autoimmune disorder to chronic pain. It acts on specific nerves and avoids significant side effects of most drugs. Closed-loop PNS neurostimulators offer the additional benefits of personalization and optimality of the treatment. Such medical devices infer physiological function from measurable nerve action potentials and deliver custom-tailored electrical stimulation to elicit desired clinical outcomes.