Silica‐Templated Metal Organic Framework‐Derived Hierarchically Porous Cobalt Oxide in Nitrogen‐Doped Carbon Nanomaterials for Electrochemical Glucose Sensing
Qiuhong Sun, Junyang Ding, Dandan Chen, Cheng Han, Minghua Jiang, Tingting Li, Yue Hu, Jinjie Qian, Shaoming Huang
Abstract
Abstract As glucose molecules are well recognized to supplement the main energy source of living cells as the intermediate product of metabolism in human body, it is of great importance to develop a convenient and quantitative glucose sensor with high selectivity, high sensitivity, and high accuracy. In this work, a simple and novel strategy has been developed to obtain a high‐performance non‐enzymatic glucose sensor by constructing hierarchically porous Co 3 O 4 embedded into the metal organic framework (MOF)‐derived N‐doped carbon matrix based on a SiO 2 template, denoted as ST‐Co 3 O 4 . The removal of the SiO 2 template creates abundant voids and a large specific surface for the obtained layered mesoporous ST‐Co 3 O 4 composite, which enhances the electron transfer kinetics and the ability to adsorb biomolecules, further greatly improving the surface reaction efficiency and promoting the improvement of its catalytic performance. Compared with pure Co 3 O 4 nanoparticles from ZIF‐67 without a silica template, as‐obtained ST‐Co 3 O 4 shows a good mesoporous environment, provides more active sites, and makes the non‐enzymatic glucose sensor exhibit high sensitivity (2860 μA mM −1 cm −2 ) and fast response time (<1 s) over a wide linear glucose concentration range of 1.0–1300.0 μM. Additionally, the ST‐Co 3 O 4 /CC electrode demonstrates good anti‐interference, high repeatability, and robust stability (>3000 s), which can repeatedly detect the glucose species in real human serum (RSD<9.69 %, n=3), and shows broad prospects in non‐enzymatic sensors.