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Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy

Tao Wan, Yuxuan Chen, Qi Pan, Xiaojie Xu, Yu Kang, Xue Gao, Feihe Huang, Chuanbin Wu, Yuan Ping

2020Journal of Controlled Release112 citationsDOI

Topics & Concepts

Genome editingCas9CRISPRKRASChemistryRibonucleoproteinSupramolecular chemistryCell biologyCancer researchBiologyBiochemistryMutationRNAGeneCrystallographyCrystal structureRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic Engineering
Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy | Litcius