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Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons

Seongsik Yun, Ben Yang, Justin D. Anair, Madison M. Martin, Stefan W. Fleps, Arin Pamukcu, Nai-Hsing Yeh, Anis Contractor, Ann Kennedy, Jones G. Parker

2023Nature Neuroscience66 citationsDOIOpen Access PDF

Topics & Concepts

Dopamine receptor D2AntipsychoticMedium spiny neuronDopamineNeurosciencePsychologyStriatumDopamine receptor D1PharmacologySchizophrenia (object-oriented programming)MedicinePsychiatryNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons | Litcius