Improving the sensitivity of <i>T</i><sub>1</sub> contrast-enhanced MRI and sensitive diagnosing tumors with ultralow doses of MnO octahedrons
Lijiao Yang, Lili Wang, Guoming Huang, Xuan Zhang, Lanlan Chen, Ao Li, Jinhao Gao, Zijian Zhou, Lichao Su, Huanghao Yang, Jibin Song
Abstract
CE-MRI of MnO nanoparticles, which can serve as a guidance for rational design of high-performance positive MRI contrast agents. Moreover, these MnO octahedrons can detect hepatic and subcutaneous tumors with an ultralow dose, hold great potential for sensitive and accurate diagnosis of cancer with lower cost, less dosages and side effects in clinic.
Topics & Concepts
Sensitivity (control systems)Contrast (vision)Nuclear magnetic resonanceChemistryMedicineNuclear medicinePhysicsOpticsElectronic engineeringEngineeringAdvanced MRI Techniques and ApplicationsMRI in cancer diagnosisLanthanide and Transition Metal Complexes