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Mechanisms, regulation and functions of the unfolded protein response

Claudio Hetz, Kezhong Zhang, Randal J. Kaufman

2020Nature Reviews Molecular Cell Biology2,608 citationsDOIOpen Access PDF

Topics & Concepts

Unfolded protein responseProteostasisEndoplasmic reticulumEndoplasmic-reticulum-associated protein degradationCell biologyProtein foldingNeurodegenerationSignal transductionCytosolBiologyDiseaseMedicineBiochemistryInternal medicineEnzymeEndoplasmic Reticulum Stress and DiseasePancreatic function and diabetesAutophagy in Disease and Therapy
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