Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
Silvia Achilli, Nathalie Berthet, Olivier Renaudet
Abstract
Antibody-recruiting molecules (ARMs) are one of the most promising tools to redirect the immune response towards cancer cells. In this review, we aim to highlight the recent advances in the field. We will illustrate the advantages of different ARM approaches and emphasize the importance of a multivalent presentation of the binding units.
Topics & Concepts
AntibodyCancerImmune systemCancer researchImmunologyBiologyGeneticsMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune ResponsesCAR-T cell therapy research