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A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease

Jay S. Schneider, Courtney A. Marshall, Lauren Keibel, Nathaniel W. Snyder, Michael P. Hill, Jonathan M. Brotchie, Tom H. Johnston, Barry D. Waterhouse, Sandhya Kortagere

2020Experimental Neurology29 citationsDOIOpen Access PDF

Topics & Concepts

DopamineNeuroscienceParkinson's diseaseLevodopaPsychologyDopamine receptor D3Prefrontal cortexDopamine transporterStriatumNorepinephrine transporterMedicineNorepinephrineCognitionDopaminergicDiseaseInternal medicineParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsNeuroscience and Neuropharmacology Research
A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease | Litcius