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The m6A methyltransferase METTL3 drives neuroinflammation and neurotoxicity through stabilizing BATF mRNA in microglia

Xun Wu, Haixiao Liu, Jin Wang, Shenghao Zhang, Qing Hu, Tinghao Wang, Wenxing Cui, Yingwu Shi, Hao Bai, Jinpeng Zhou, Liying Han, Leiyang Li, Tianzhi Zhao, Yang Wu, Jianing Luo, Dayun Feng, Wei Guo, Shunnan Ge, Yan Qu

2024Cell Death and Differentiation56 citationsDOIOpen Access PDF

Topics & Concepts

NeuroinflammationMicrogliaNeurotoxicityUbiquitin ligaseTraumatic brain injuryUbiquitinMedicineCancer researchBiologyImmunologyInflammationCell biologyNeuroscienceInternal medicineGeneGeneticsToxicityPsychiatryRNA modifications and cancerCancer-related gene regulationCancer-related molecular mechanisms research