De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia
GROUP Investigators, Elliott Rees, Jun Han, Joanne Morgan, Noa Carrera, Valentina Escott‐Price, Andrew Pocklington, Madeleine Duffield, Lynsey S. Hall, Sophie E. Legge, Antonio F. Pardiñas, Alexander Richards, Julian Roth, Tatyana Lezheiko, Nikolay Kondratyev, Василий Глебович Каледа, В. Е. Голимбет, Mara Parellada, Javier González‐Peñas, Celso Arango, Micha Gawlik, George Kirov, James Walters, Peter Holmans, Michael O‘Donovan, Michael J. Owen
Topics & Concepts
ProbandExome sequencingGeneticsMissense mutationExomeBiologyGeneLoss functionSchizophrenia (object-oriented programming)AlleleNeurodevelopmental disorderBipolar disorderMutationPhenotypeMedicineNeurosciencePsychiatryCognitionGenetic Associations and EpidemiologyGenomic variations and chromosomal abnormalitiesGenomics and Rare Diseases