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Nanoconfined anti-oxidizing RAFT nitroxide radical polymer for reduction of low-density lipoprotein oxidation and foam cell formation

Suman Basak, Harshvardhan Ajay Khare, Paul J. Kempen, Nazila Kamaly, Kristoffer Almdal

2022Nanoscale Advances24 citationsDOIOpen Access PDF

Abstract

). Finally, the nitroxide NPs has been shown to inhibit foam cell formation in macrophages by decreasing internalization of oxidized low-density lipoproteins.

Topics & Concepts

ChemistryRaftReactive oxygen speciesGlycidyl methacrylateAntioxidantChain transferMethacrylateCopolymerRadical polymerizationSuperoxide dismutaseBiophysicsPolymerizationFoam cellOxygen radical absorbance capacityPolymer chemistryPolymerOrganic chemistryBiochemistryLipoproteinCholesterolDPPHBiologyElectron Spin Resonance StudiesAntioxidant Activity and Oxidative StressFree Radicals and Antioxidants
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