CRISPR/Cas systems to overcome challenges in developing the next generation of T cells for cancer therapy
Dennis Huang, Matthew S. Miller, Bhaargavi Ashok, Samagra Jain, Nicholas A. Peppas
Topics & Concepts
CRISPRChimeric antigen receptorGenome editingComputational biologyImmune systemTumor microenvironmentBiologyImmunotherapyGenetic enhancementCancerCell therapyT-cell receptorMultiplexT cellCancer researchImmunologyMedicineBioinformaticsStem cellGeneGeneticsCAR-T cell therapy researchCRISPR and Genetic EngineeringNanowire Synthesis and Applications