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Oligosaccharides derived from <i>Lycium barbarum</i> ameliorate glycolipid metabolism and modulate the gut microbiota community and the faecal metabolites in a type 2 diabetes mouse model: metabolomic bioinformatic analysis

Hao Liu, Zheng Zhang, Jianpeng Li, Wei Liu, Mohamad Warda, Bo Cui, A.M. Abd El‐Aty

2022Food & Function26 citationsDOI

Abstract

, and maintained intestinal barrier integrity. The faecal metabolic map showed that the contents of glycogen amino acids, such as proline, serine, and leucine, increased. The contents of cholic, capric, and dodecanoic acid decreased. In summary, we may suggest that LBO can be used as a prebiotic for treating T2D.

Topics & Concepts

AkkermansiaPrebioticGut floraBacteroidesPrevotellaMetabolomicsBiologyMicrobiomeType 2 diabetesLyciumBiochemistryResistant starchInsulin resistanceLipid metabolismCarbohydrate metabolismLeucineMicrobiologyBacteriaDiabetes mellitusEndocrinologyAmino acidMedicineStarchBioinformaticsAlternative medicineGeneticsPathologyGut microbiota and healthProbiotics and Fermented FoodsDiet, Metabolism, and Disease
Oligosaccharides derived from <i>Lycium barbarum</i> ameliorate glycolipid metabolism and modulate the gut microbiota community and the faecal metabolites in a type 2 diabetes mouse model: metabolomic bioinformatic analysis | Litcius