<i>N</i>-Heterocyclic Carbene Gold(I) Complexes: Mechanism of the Ligand Scrambling Reaction and Their Oxidation to Gold(III) in Aqueous Solutions
Sina Katharina Goetzfried, Caroline Marie Gallati, Monika Cziferszky, Radu A. Talmazan, Klaus Wurst, Klaus R. Liedl, Maren Podewitz, Ronald Gust
Abstract
Br complex differs from that found for related silver(I) analogous. A detailed understanding of this scrambling mechanism is of utmost importance for the interpretation of their biological activity and will help to further optimize them for biomedical and other applications.
Topics & Concepts
ChemistryCarbeneAcetonitrileLigand (biochemistry)ScramblingDimerDissociation (chemistry)Aqueous solutionCombinatorial chemistryReaction mechanismRedoxStereochemistryMedicinal chemistryComputational chemistryOrganic chemistryCatalysisReceptorPhilosophyLinguisticsBiochemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCatalytic Alkyne Reactions