Photoinduced Dehalocyclization to Access Oxindoles Using Formate as a Reductant
Wei Ge, Jiaxin Wang, Ming‐Chen Fu, Yao Fu
Abstract
Comprehensive Summary Herein, we report an efficient and practical protocol for the photoinduced dehalocyclization of ortho ‐halophenylacrylamides with formate by the engagement of a CO 2 radical anion to access substituted oxindoles. This method proceeds smoothly under mild conditions and exhibits a wide range of substrate as well as remarkable functional group compatibility.
Topics & Concepts
ChemistryFormateCombinatorial chemistryIonFunctional groupPhotochemistryCatalysisOrganic chemistryPolymerRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry