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Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study

Ali Eman, Onur Balaban, Havva Kocayiğit, Kezban Özmen Süner, Yaşar Cırdı, Ali Fuat Erdem

2021Journal of Korean Medical Science15 citationsDOIOpen Access PDF

Abstract

BACKGROUND: We assessed maternal and neonatal outcomes of critically ill pregnant and puerperal patients in the clinical course of coronavirus disease 2019 (COVID-19). METHODS: Records of pregnant and puerperal women with polymerase chain reaction positive COVID-19 virus who were admitted to our intensive care unit (ICU) from March 2020 to August 2021 were investigated. Demographic, clinical and laboratory data, pharmacotherapy, and neonatal outcomes were analyzed. These outcomes were compared between patients that were discharged from ICU and patients who died in ICU. RESULTS: = 0.024). Eleven preterm (57.8%) and eight term deliveries (42.1%) occurred. CONCLUSION: High mortality rate was detected among critically ill pregnant/parturient patients followed in the ICU. Main predictors of mortality were the need of invasive mechanical ventilation and higher number of days hospitalized in ICU. Rate of C/S operations and preterm delivery were high. Pleasingly, the rate of neonatal death was low and no neonatal COVID-19 occurred.

Topics & Concepts

MedicineRetrospective cohort studyCritically illCoronavirus disease 2019 (COVID-19)PregnancyDiseaseObstetrics2019-20 coronavirus outbreakPandemicIntensive care medicineBetacoronavirusPuerperal InfectionPediatricsInternal medicineInfectious disease (medical specialty)VirologyOutbreakGeneticsBiologyCOVID-19 Impact on ReproductionGestational Diabetes Research and ManagementCOVID-19 and healthcare impacts