<i>In vivo</i> imaging of CD8<sup>+</sup> T cells in metastatic cancer patients: first clinical experience with simultaneous [<sup>89</sup>Zr]Zr-Df-IAB22M2C PET/MRI
Johannes Schwenck, Dominik Sonanini, Dominik Seyfried, Walter Ehrlichmann, Gabriele Kienzle, Gerald Reischl, Pascal Krezer, Ian A. Wilson, Ron Korn, Irene González-Menéndez, Leticia Quintanilla‐Martínez, Ferdinand Seith, Andrea Forschner, Thomas Eigentler, Lars Zender, Martin Röcken, Bernd J. Pichler, Lukas Flatz, Manfred Kneilling, Christian la Fougère
Abstract
Zr]Zr-Df-IAB22M2C uptake in primary and secondary lymphoid organs might be associated with the response to ICT.
Topics & Concepts
In vivoCD8MedicineCancerCytotoxic T cellNuclear medicineIn vitroCancer researchPathologyAntigenChemistryInternal medicineImmunologyBiologyBiochemistryBiotechnologyCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmunotherapy and Immune Responses