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Walking or body weight squat “activity snacks” increase dietary amino acid utilization for myofibrillar protein synthesis during prolonged sitting

Daniel R. Moore, Eric Williamson, Nathan Hodson, Stephanie Estafanos, Michael Mazzulla, Dinesh Kumbhare, Jenna B. Gillen

2022Journal of Applied Physiology16 citationsDOI

Abstract

Prolonged sitting can impair postprandial glycemia, lipidemia, and insulin sensitivity regardless of previous health status. We demonstrate that interrupting prolonged sitting with brief periods of activity, such as body weight squats or short bouts of walking, improves the efficiency of dietary amino acid utilizations for muscle contractile protein synthesis. This further emphasizes the importance of minimizing sedentary time to improve the postprandial metabolism of all macronutrients.

Topics & Concepts

PostprandialSquatSittingMyofibrilEndocrinologyInternal medicineAmino acidBody weightMedicineChemistryAnimal scienceBiochemistryBiologyPhysical therapyDiabetes mellitusPathologyMuscle metabolism and nutritionSports Performance and TrainingCardiovascular and exercise physiology
Walking or body weight squat “activity snacks” increase dietary amino acid utilization for myofibrillar protein synthesis during prolonged sitting | Litcius