<sup>161</sup>Tb-PSMA Radioligand Therapy: First-in-Humans SPECT/CT Imaging
Akram Al‐Ibraheem, Rahma M. Doudeen, Diyaa Juaidi, Alaa Abufara, Stephan Maus
Abstract
Terbium-161 is a β-emitting radionuclide that resembles 177Lu in terms of its in vivo and in vitro chemical and pharmacokinetic properties, exhibiting similar behavior with regard to radioligand-specific cell uptake and internalization, as well as emitting a modest fraction of photons useful for
Topics & Concepts
RadioligandInternalizationRadiochemistryNuclear medicineSpect imagingIn vivoTerbiumChemistryRadiosynthesisRadionuclideRadionuclide therapyPharmacokineticsIn vitroMedicinePositron emission tomographyPharmacologyCellPhysicsBiologyBiochemistryNuclear physicsOrganic chemistryIonBiotechnologyRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsProstate Cancer Treatment and Research