Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice
Yiying Wang, Yuning Zhou, Lin Jiang, Shun Wang, Lin Zhu, Shanshan Zhang, Hao Yang, Qi He, Li Liu, Yuhan Xie, Xin Liang, Jing Tang, Feng‐lei Chao, Yong Tang
Topics & Concepts
Dendritic spineColocalizationMicrogliaHippocampal formationSynapsin IHippocampusGenetically modified mouseSynapseRage (emotion)Dentate gyrusInternal medicineEndocrinologyGlycationTransgeneBiologyNeuroscienceMedicineReceptorInflammationBiochemistryGeneSynaptic vesicleMembraneVesicleNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsAdvanced Glycation End Products research