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A Community-transmitted Case of Severe Acute Respiratory Distress Syndrome (SARS) Due to SARS-CoV-2 in the United States

Bradley Sanville, R. Corbett, Wesley Pidcock, Kaitlyn Hardin, Christian Sebat, Minh-Vu H Nguyen, George R. Thompson, Angela Haczku, Michael Schivo, Stuart Cohen

2020Clinical Infectious Diseases28 citationsDOIOpen Access PDF

Abstract

This is the first known community transmission case of the novel coronavirus disease (COVID-19) in the United States, with significant public health implications. Diagnosis of COVID-19 is currently confirmed with PCR based testing of appropriate respiratory samples. Given the absence of travel or known exposure history, this patient did not meet the criteria for testing according to CDC guidelines at the time of her presentation. Since this case, any patient with severe disease (eg, ARDS or pneumonia) requiring hospitalization without an explanatory diagnosis can be tested even if no clear source of exposure is identified. While influencing national health policies for revising screening criteria, this case also highlighted significant knowledge gaps in diagnosis and treatment and a desperate need for early, widespread, fast and cheap testing for COVID-19.

Topics & Concepts

ARDSMedicineCoronavirus disease 2019 (COVID-19)PneumoniaIntensive care medicinePublic healthDiseaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Acute respiratory distressDiagnostic testTransmission (telecommunications)PandemicEmergency medicineInfectious disease (medical specialty)Internal medicineLungPathologyElectrical engineeringEngineeringCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19