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Cell stress in cortical organoids impairs molecular subtype specification

Aparna Bhaduri, Madeline G. Andrews, Walter Mancia, Diane Jung, David Shin, Denise E. Allen, Dana Jung, Galina Schmunk, Maximilian Haeussler, Jahan Salma, Alex A. Pollen, Tomasz J. Nowakowski, Arnold R. Kriegstein

2020Nature641 citationsDOIOpen Access PDF

Topics & Concepts

OrganoidBiologyProgenitor cellNeuroscienceTranscriptomeProgenitorCorticogenesisCell typeCell biologyHuman brainCortex (anatomy)CellCortical neuronsStem cellGeneGene expressionGeneticsPluripotent Stem Cells ResearchSingle-cell and spatial transcriptomicsRNA Research and Splicing
Cell stress in cortical organoids impairs molecular subtype specification | Litcius