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Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents

Mohamed Ayman El‐Zahabi, Helmy Sakr, Khaled El‐Adl, Mohamed F. Zayed, Adel S. Abdelraheem, Sally I. Eissa, Hazem Elkady, Ibrahim H. Eissa

2020Bioorganic Chemistry103 citationsDOI

Topics & Concepts

ThalidomideChemistryApoptosisTumor necrosis factor alphaIn vitroCell cycle checkpointCytotoxicityIC50Cytotoxic T cellCell cycleCell culturePharmacologyBiochemistryImmunologyBiologyMultiple myelomaGeneticsMultiple Myeloma Research and TreatmentsCancer therapeutics and mechanismsBeetle Biology and Toxicology Studies
Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents | Litcius