TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra J. McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P. Patel, Michael T. Werner, Alexander C. Huang, Katherine A. Alexander, Jennifer E. Wu, John Attanasio, Patrick Yan, Sangeeth M. George, Bertram Bengsch, Ryan P. Staupe, Greg Donahue, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Jonathan Kaye, Shelley L. Berger, E. John Wherry