Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication
Shuang Tang, Jie Li, Yung‐Fu Chang, Wencheng Lin
Abstract
Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent vaccination against other diseases. There is growing evidence showing the interaction between ALV and the host. In this review, we will survey the present knowledge of the involvement of host factors in the important molecular events during ALV infection and discuss the futuristic perspectives from this angle.
Topics & Concepts
LeucosisHost (biology)Host factorsImmunosuppressionVirusVirologyBiologyViral replicationImmunologyGeneticsinterferon and immune responsesHerpesvirus Infections and TreatmentsAnimal Virus Infections Studies