Litcius/Paper detail

Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer’s disease agents

Hongwei Gao, Yingying Jiang, Jiuyu Zhan, Yingni Sun

2021Bioorganic Chemistry65 citationsDOI

Topics & Concepts

PharmacophoreChemistryButyrylcholinesteraseAcetylcholinesteraseAchéDrugPharmacologyDiseaseCombinatorial chemistryBiochemistryEnzymeMedicineInternal medicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsPhosphodiesterase function and regulation