Synthesis of Rh<sup>III</sup> and Ir<sup>III</sup> Complexes Bearing Chelating Di-NHC Ligands Obtained from N9-Imidazolium-Substituted Adenine
Rebeca Nayely Osorio Yáñez, Alexander Hepp, Tristan Tsai Yuan Tan, F. Ekkehardt Hahn
Abstract
The N9-imidazolium-substituted adenine derivative H-1Cl reacts with [MCl2(Cp*)]2 (M = Rh, Ir) in acetonitrile at 75 °C with formation of the CNHC^N3adenine chelate complexes [3]Cl and [4]Cl, respectively. At higher temperature (125 °C), double deprotonation of H-1Cl by NaOAc was observed and the reaction with [MCl2(Cp*)]2 (M = Rh, Ir) yields the chelate complexes [5] and [6] bearing a unique CNHC^Cazolato chelate ligand. The N7-protonation of the ring-nitrogen atoms of the azolato donor in [5] and [6] was also performed to give the complexes bearing a CNHC^CpNHC chelate ligand.
Topics & Concepts
ChemistryChelationDeprotonationProtonationLigand (biochemistry)Medicinal chemistryAcetonitrileDerivative (finance)Ring (chemistry)StereochemistryInorganic chemistryOrganic chemistryIonReceptorEconomicsFinancial economicsBiochemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsOrganoboron and organosilicon chemistry