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Synthesis and evaluation of 18F labeled crizotinib derivative [18F]FPC as a novel PET probe for imaging c-MET-positive NSCLC tumor

Qingyu Lin, Yingying Zhang, Zhequan Fu, Bingxin Hu, Zhan Si, Yanzhao Zhao, Hongcheng Shi, Dengfeng Cheng

2020Bioorganic & Medicinal Chemistry24 citationsDOI

Topics & Concepts

CrizotinibChemistryPet imagingLung cancerPositron emission tomographyMolecular imagingC-MetCancer researchOncologyMedicineInternal medicineNuclear medicineReceptorIn vivoBiotechnologyMalignant pleural effusionBiologyHepatocyte growth factorLung Cancer Treatments and MutationsRadiopharmaceutical Chemistry and ApplicationsHepatocellular Carcinoma Treatment and Prognosis
Synthesis and evaluation of 18F labeled crizotinib derivative [18F]FPC as a novel PET probe for imaging c-MET-positive NSCLC tumor | Litcius