Postsynthetic Modification of Amine-Functionalized MIL-101(Cr) Metal–Organic Frameworks with an EDTA–Zn(II) Complex as an Effective Heterogeneous Catalyst for Hantzsch Synthesis of Polyhydroquinolines
Ahmad Nikseresht, Fatemeh Ghoochi, Masoud Mohammadi
Abstract
High Resolution Image Download MS PowerPoint Slide The present work aims at preparing the EDTA–Zn(II) complex─supported on the amine-functionalized MIL-101(Cr) MOF─as a new and effective heterogenized catalyst. The optimization of the hydrothermal process shows that 120 °C is the best condition to grow the MIL-101(Cr)–NH 2 MOF crystals. Moreover, regarding the use of the postsynthetic modification (PSM) method, hexadentate EDTA was grafted on this support via a simple aminolysis process before further coordinating it with Zn ions to create the corresponding Zn(II) catalytic complex. The catalytic activity of this compound was then investigated in the context of a one-pot synthesis of polyhydroquinolines. This approach has a number of advantages including the following: the use of a solvent that is not hazardous, applying a porous catalyst that is inexpensive, secure, and recyclable; rapid reaction times, high levels of efficiency, and the simplicity of MOF catalyst separation. Accordingly, the process in question can be given the label of “green chemistry”.