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Case of Carbapenem-Resistant <i>Salmonella</i> Typhi Infection, Pakistan, 2022

Summiya Nizamuddin, Ejaz Ahmad Khan, Marie Anne Chattaway, Gauri Godbole

2023Emerging infectious diseases26 citationsDOIOpen Access PDF

Abstract

Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous meropenem and colistin was successful. Carbapenem-resistant Salmonella Typhi emergence will hinder treatment.

Topics & Concepts

Salmonella typhiMeropenemCarbapenemColistinAzithromycinMedicineMicrobiologySalmonellaVirologyBiologyAntibioticsBacteriaAntibiotic resistanceGeneEscherichia coliBiochemistryGeneticsSalmonella and Campylobacter epidemiologyVibrio bacteria research studiesAntibiotic Resistance in Bacteria
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