Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production
Yue Shan, Zhao Tong, Jinzhu Ma, Yu Liu, Zhang Zecai, Chenhua Wu, Wenjing Huang, Siyu Liu, Chen Nannan, Su Siyu, Tongtong Bai, Huang Jiang, Bai Biaohui, Xin Jin, Zhou Yulong, Zhanbo Zhu
Topics & Concepts
BiologyMDA5InterferonIRF3VirologyInnate immune systemVirusSendai virusViral replicationProtein kinase RSignal transductionImmune systemCell biologyRNAProtein kinase CGeneRNA interferenceBiochemistryImmunologyMitogen-activated protein kinase kinaseAnimal Disease Management and EpidemiologyImmune Cell Function and InteractionViral Infections and Vectors