Discovery of 1,3,4-oxadiazole derivatives containing a bisamide moiety as a novel class of potential cardioprotective agents
Feifei Yang, Jin-Zhu Zhou, Xue-Li Xu, Ting Hu, Jianquan Liu, Ya‐Xi Wu, Bo Wei, Liying Ma
Topics & Concepts
PharmacophoreChemistryOxidative stressMoietyCytotoxicityAntioxidantPharmacologyOxadiazoleApoptosisOxidative phosphorylationStructure–activity relationshipBiochemistryStereochemistryMedicineIn vitroOrganic chemistryChemotherapy-induced cardiotoxicity and mitigationSynthesis and Biological EvaluationMetal complexes synthesis and properties