Modification of osimertinib to discover new potent EGFRC797S-TK inhibitors

Xiao-Xiao Xi, Hongyi Zhao, Yu-Ze Mao, Minhang Xin, San‐Qi Zhang

2023European Journal of Medicinal Chemistry19 citationsDOI Open Access PDF

Topics & Concepts

T790MOsimertinibChemistryPharmacologyIC50Cancer researchIn vitroBiochemistryEpidermal growth factor receptorReceptorGefitinibMedicineErlotinibLung Cancer Treatments and MutationsCancer therapeutics and mechanismsColorectal Cancer Treatments and Studies