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Development of a Simple and Stable NanoESI Spray System Using Suction Wind from the MS Inlet

Yusuke Kawashima, M. Ishikawa, Ryo Konno, Daisuke Nakajima, Osamu Ohara

2023Journal of Proteome Research19 citationsDOI

Abstract

Improving the reproducibility of proteome analysis systems presents a challenge; therefore, in this study, we developed a new insertion spray ionization (InSpIon) system wherein an InSpIon tube was designed with a spray tip inserted into the tube. This system stabilized the spray and subsequently improved the reproducibility of the analysis.

Topics & Concepts

ReproducibilityInletTube (container)SuctionChromatographyMaterials scienceProteomeChemistryEngineeringMechanical engineeringComposite materialBiochemistryAdvanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and ApplicationsBiosensors and Analytical Detection
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