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PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection

Christopher Ritchie, Lingyin Li

2024Molecular Cell12 citationsDOIOpen Access PDF

Topics & Concepts

StingIRF3Stimulator of interferon genesBiologyTANK-binding kinase 1InterferonInnate immune systemRegulatorCell biologySignal transductionULK1Immune systemDownregulation and upregulationTranscription factorImmunologyCancer researchPhosphorylationProtein kinase AGeneGeneticsAMPKEngineeringAerospace engineeringMitogen-activated protein kinase kinaseinterferon and immune responsesViral Infections and VectorsRNA regulation and disease
PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection | Litcius