Peritoneal dissemination of breast cancer diagnosed by laparoscopy
Tsuyoshi Nakagawa, Goshi Oda, Akifumi Kikuchi, Toshifumi Saito, Tomoyuki Fujioka, Kazunori Kubota, M. Mori, Iichiroh Onishi, Hiroyuki Uetake
Abstract
The accuracy of modern imaging techniques for the diagnosis of peritoneal carcinomatosis is poor. A breast cancer patient with a high serum CA15-3 level did not receive a definitive diagnosis of peritoneal dissemination by imaging examination and then underwent laparoscopy. Pathological examination showed peritoneal dissemination of breast cancer, but the biological markers were different from the primary lesion: ER(-), PgR(-), and Her2:3 +. T-DM1 therapy was very effective, and her systemic symptoms disappeared. Since biomarkers of metastatic lesions may sometimes change, laparoscopic biopsy is very important and useful.