A sustained-release PDGF-BB nanocomposite hydrogel for DM-associated bone regeneration
Yaxin Li, Ziyang Liu, Chen Zhao, Chenci Xu, Airi Shin, Jiaqing Wu, Dejian Li, Kaili Lin, Jiaqiang Liu
Abstract
). This injectable hydrogel heals calvarial lesions successfully in diabetic rats and has the potential to be used as a direct and effective tool for treating diabetic patients.
Topics & Concepts
Regeneration (biology)Platelet-derived growth factor receptorBone healingControlled releaseCell biologyMAPK/ERK pathwayStem cellMaterials scienceChemistryCancer researchPharmacologyMedicineInternal medicineGrowth factorSignal transductionBiologySurgeryReceptorBone Tissue Engineering MaterialsGraphene and Nanomaterials ApplicationsMesenchymal stem cell research