Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells
Restituto Tocmo, Bryan Le, Amber Heun, Jan Peter van Pijkeren, Kirk L. Parkin, Jeremy J. Johnson
Topics & Concepts
Garcinia mangostanaAryl hydrocarbon receptorChemistryGarciniaReactive oxygen speciesOxidative stressPrenylationOccludinBiochemistrySignal transductionCell biologyPharmacologyTight junctionBiologyTranscription factorBotanyTraditional medicineEnzymeGeneMedicineNatural Compound Pharmacology StudiesBioactive natural compoundsBioactive Compounds and Antitumor Agents