CHO cell productivity improvement by genome-scale modeling and pathway analysis: Application to feed supplements
Zhuangrong Huang, Jianlin Xu, Andrew Yongky, Caitlin Morris, Ashli Polanco, Michael D. Reily, Michael Borys, Zheng Jian Li, Seongkyu Yoon
Topics & Concepts
BioprocessFlux balance analysisIn silicoBiochemical engineeringChinese hamster ovary cellComputational biologyBioreactorProcess (computing)Bioprocess engineeringComputer scienceSystems biologyProcess optimizationMetabolic flux analysisBiologyBiotechnologyBiological systemCell cultureEngineeringGeneticsBiochemistryGeneMetabolismOperating systemEnvironmental engineeringPaleontologyBotanyViral Infectious Diseases and Gene Expression in InsectsMicrobial Metabolic Engineering and Bioproductionthermodynamics and calorimetric analyses