The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation
Yanyan Zhang, Li He, Mengxin Tu, Mei Huang, Yan Chen, Di Pan, Jianqing Peng, Xiangchun Shen
Topics & Concepts
Gene knockdownVascular smooth muscleSirtuin 1Unfolded protein responseDownregulation and upregulationChemistryATF4CalcificationAcetylationEndoplasmic reticulumEndocrinologyInternal medicineIn vivoOxidative stressCell biologyApoptosisCancer researchBiologyMedicineBiochemistrySmooth muscleBiotechnologyGeneEndoplasmic Reticulum Stress and DiseaseSirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy