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Emerging role of exosomes in craniofacial and dental applications

Xin Xing, Shuang Han, Zhi Li, Zubing Li

2020Theranostics47 citationsDOIOpen Access PDF

Abstract

Exosomes, a specific subgroup of extracellular vesicles that are secreted by cells, have been recognized as important mediators of intercellular communication. They participate in a diverse range of physiological and pathological processes. Given the capability of exosomes to carry molecular cargos and transfer bioactive components, exosome-based disease diagnosis and therapeutics have been extensively studied over the past few decades. Herein, we highlight the emerging applications of exosomes as biomarkers and therapeutic agents in the craniofacial and dental field. Moreover, we discuss the current challenges and future perspectives of exosomes in clinical applications.

Topics & Concepts

MicrovesiclesExtracellular vesiclesExosomeCraniofacialMedicineBiologyCell biologyComputational biologyBioinformaticsmicroRNAGeneticsGeneExtracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene Delivery