Emerging role of exosomes in craniofacial and dental applications
Xin Xing, Shuang Han, Zhi Li, Zubing Li
Abstract
Exosomes, a specific subgroup of extracellular vesicles that are secreted by cells, have been recognized as important mediators of intercellular communication. They participate in a diverse range of physiological and pathological processes. Given the capability of exosomes to carry molecular cargos and transfer bioactive components, exosome-based disease diagnosis and therapeutics have been extensively studied over the past few decades. Herein, we highlight the emerging applications of exosomes as biomarkers and therapeutic agents in the craniofacial and dental field. Moreover, we discuss the current challenges and future perspectives of exosomes in clinical applications.
Topics & Concepts
MicrovesiclesExtracellular vesiclesExosomeCraniofacialMedicineBiologyCell biologyComputational biologyBioinformaticsmicroRNAGeneticsGeneExtracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene Delivery