A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes
Mahmoud I. Abdel‐Aziz, Susanne J. H. Vijverberg, Anne H. Neerincx, Paul Brinkman, Ariane H. Wagener, John Riley, Ana R. Sousa, Stewart Bates, Scott Wagers, Bertrand De Meulder, Charles Auffray, Åsa M. Wheelock, Aruna T. Bansal, Massimo Caruso, Pascal Chanez, Mohib Uddin, Julie Corfield, Ildikó Horváth, Norbert Krug, Jacek Musiał, Kai Sun, Dominick Shaw, Thomas Sandström, Paolo Montuschi, Stephen J. Fowler, René Lutter, Ratko Djukanović, Peter Howarth, Paul Skipp, Marek Sanak, Ian M. Adcock, Kian Fan Chung, Peter J. Sterk, Aletta D. Kraneveld, Anke H. Maitland‐van der Zee
Abstract
<b>A multi-omics approach revealed the underlying biological pathways in the microbiome-driven severe asthma phenotypes. This may help to elucidate new leads for treatment development, particularly for the therapeutically challenging neutrophilic asthma.</b>https://bit.ly/3FWuJqS