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A transition to stable one-dimensional swimming enhances E. coli motility through narrow channels

Gaszton Vizsnyiczai, Giacomo Frangipane, S. Bianchi, Filippo Saglimbeni, Dario Dell’Arciprete, Roberto Di Leonardo

2020Nature Communications48 citationsDOIOpen Access PDF

Abstract

Living organisms often display adaptive strategies that allow them to move efficiently even in strong confinement. With one single degree of freedom, the angle of a rotating bundle of flagella, bacteria provide one of the simplest examples of locomotion in the living world. Here we show that a purely physical mechanism, depending on a hydrodynamic stability condition, is responsible for a confinement induced transition between two swimming states in E. coli. While in large channels bacteria always crash onto confining walls, when the cross section falls below a threshold, they leave the walls to move swiftly on a stable swimming trajectory along the channel axis. We investigate this phenomenon for individual cells that are guided through a sequence of micro-fabricated tunnels of decreasing cross section. Our results challenge current theoretical predictions and suggest effective design principles for microrobots by showing that motility based on helical propellers provides a robust swimming strategy for exploring narrow spaces.

Topics & Concepts

FlagellumMechanism (biology)TrajectoryChannel (broadcasting)BundlePhysicsTransition (genetics)MechanicsBiophysicsComputer scienceNanotechnologyControl theory (sociology)BiologyMaterials scienceBacteriaArtificial intelligenceTelecommunicationsBiochemistryComposite materialGeneticsAstronomyControl (management)Quantum mechanicsGeneMicro and Nano RoboticsMolecular Communication and NanonetworksMicrofluidic and Bio-sensing Technologies
A transition to stable one-dimensional swimming enhances E. coli motility through narrow channels | Litcius