Development of a Thermosensitive In-Situ Gel Formulations of Vancomycin Hydrochloride: Design, Preparation, In Vitro and In Vivo Evaluation
Luyu Bai, Fang Lei, Rui Luo, Qingsong Fei, Zhiyun Zheng, Ning He, Shuangying Gui
Topics & Concepts
BioavailabilityPoloxamerVancomycinPharmacokineticsChromatographyDrug deliveryIn vivoPharmacologyPoloxamer 407Differential scanning calorimetryDosage formChemistryMedicineStaphylococcus aureusPolymerOrganic chemistryBacteriaGeneticsBiologyBiotechnologyPhysicsThermodynamicsCopolymerAdvanced Drug Delivery SystemsOcular Surface and Contact LensProtein Interaction Studies and Fluorescence Analysis