Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis
Junjun Long, Tianhao Ying, Lei Zhang, Tao Yu, Jinhui Wu, Yasen Liu, Xiaoli Li, Guoliang You, Leiming Zhang, Yi Bi
Topics & Concepts
PharmacologyIn vivoStingSepsisChemistryLipopolysaccharideStimulator of interferon genesNitric oxideIRF3MedicineImmunologyBiochemistryInnate immune systemBiologyReceptorBiotechnologyAerospace engineeringEngineeringOrganic chemistryinterferon and immune responsesImmune Response and InflammationInflammasome and immune disorders