Precision Surgery and Kidney Cancer: Knowledge of Genetic Alterations Influences Surgical Management
Patrick T. Gomella, W. Marston Linehan, Mark W. Ball
Abstract
Renal cell carcinoma is a term that represents multiple different disease processes, each driven by different genetic alterations, with distinct histology, and biological potential which necessitates divergent management strategies. This review discusses the genetic alterations seen in several forms of hereditary kidney cancer and how that knowledge can dictate when and how to intervene with a focus on the surgical management of these tumors.
Topics & Concepts
Kidney cancerRenal cell carcinomaCancerDiseaseKidneyMedicineBioinformaticsBiologyPathologyInternal medicineRenal cell carcinoma treatmentRenal and related cancersGenetic and Kidney Cyst Diseases