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riboCIRC: a comprehensive database of translatable circRNAs

Huihui Li, Mingzhe Xie, Yan Wang, Ludong Yang, Zhi Xie, Hongwei Wang

2021Genome biology83 citationsDOIOpen Access PDF

Abstract

riboCIRC is a translatome data-oriented circRNA database specifically designed for hosting, exploring, analyzing, and visualizing translatable circRNAs from multi-species. The database provides a comprehensive repository of computationally predicted ribosome-associated circRNAs; a manually curated collection of experimentally verified translated circRNAs; an evaluation of cross-species conservation of translatable circRNAs; a systematic de novo annotation of putative circRNA-encoded peptides, including sequence, structure, and function; and a genome browser to visualize the context-specific occupant footprints of circRNAs. It represents a valuable resource for the circRNA research community and is publicly available at http://www.ribocirc.com .

Topics & Concepts

BiologyAnnotationComputational biologyContext (archaeology)GenomeDatabaseBioinformaticsComputer scienceGeneticsGenePaleontologyCircular RNAs in diseasesRNA modifications and cancerSemiconductor materials and interfaces
riboCIRC: a comprehensive database of translatable circRNAs | Litcius