Curcumin–polymer conjugates with dynamic boronic acid ester linkages for selective killing of cancer cells
Ruihao Pan, Yuan Zeng, Guoqiang Liu, Yen Wei, Yanshuang Xu, Lei Tao
Abstract
A phenylboronic acid (PBA)-containing copolymer was synthesized <italic>via</italic> the Hantzsch reaction and radical polymerization. Curcumin was dynamically included in this PBA-containing polymer to selectively kill cancer cells.
Topics & Concepts
Phenylboronic acidCurcuminBoronic acidChemistryConjugatePolymerizationCombinatorial chemistryPolymerCancer cellCopolymerOrganic chemistryCancerBiochemistryCatalysisBiologyGeneticsMathematical analysisMathematicsCurcumin's Biomedical ApplicationsRNA Interference and Gene DeliverySupramolecular Self-Assembly in Materials