First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart
Aaron Olson, Bertrand Bouchard, Wei Zhu, John C. Chatham, Christine Des Rosiers
Abstract
perfused heart, HBP flux does not respond to acute changes in glucose availability or cardiac workload.
Topics & Concepts
Flux (metallurgy)GlycolysisBiosynthesisEx vivoChemistryIn vivoInternal medicineBiochemistryEndocrinologyMetabolismCarbohydrate metabolismEnzymeIn vitroBiologyMedicineOrganic chemistryBiotechnologyGlycosylation and Glycoproteins ResearchProteoglycans and glycosaminoglycans researchCarbohydrate Chemistry and Synthesis