Litcius/Paper detail

Role of cyanuric chloride in organic synthesis: A concise overview

Ayushi Sethiya, Dinesh Kumar Jangid, Joohee Pradhan, Shikha Agarwal

2023Journal of Heterocyclic Chemistry24 citationsDOI

Abstract

Abstract Cyanuric chloride, a chlorinated analog of 1,3,5‐triazine, is used as a catalyst, promoter, and activator to catalyze and initiate several reactions like Beckmann rearrangement, Lossen rearrangement, Biginelli reaction, Suzuki coupling reaction, Pictet Spengler reaction, Mannich reaction, etc. It is employed in several reactions due to its several properties like stable, non‐volatile, cost‐efficient, easy to handle, and easy commercial availability. Moreover, it is a very renowned precursor for the synthesis of triazine‐class pesticide atrazine, dyes, and crosslinking agents. Herein in this review article, the reactions initiated, catalyzed, and promoted by cyanuric chloride from 2010 to 2022 have been elaborated.

Topics & Concepts

Cyanuric chlorideChemistryTriazineCatalysisCombinatorial chemistryOrganic chemistryChlorideOrganic synthesisReaction conditionsCoupling reactionSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological EvaluationSynthesis of heterocyclic compounds